Glenn Cruse, PhD | Principal Investigator
Associate Professor of Immunology
Dr. Cruse completed his Ph.D. with Professor Peter Bradding at Glenfield Hospital, The University of Leicester, UK in 2009. He then moved to the National Institutes of Health in Bethesda, Maryland, in January 2010 to start a visiting postdoctoral fellowship in the Laboratory of Allergic Diseases, NIAID, with Dr. Dean Metcalfe. In January 2015, Dr. Cruse was appointed as a Research Fellow in the same laboratory, and in January 2016, he joined the Department of Molecular Biomedical Sciences at NC State University as an Assistant Professor. Dr. Cruse was awarded Tenure and promoted to Associate Professor in 2023 in the same department.
Dr. Cruse is a mast cell biologist who has authored and co-authored over 30 publications including articles in top journals such as the New England Journal of Medicine, Proceedings of the National Academy of Sciences USA and Immunity. The Cruse lab is interested in the role that mast cells play in allergic and inflammatory diseases and identifying novel therapeutics that target mast cells. Since mast cells act as sentinel cells that participate in both innate and acquired immunity, particularly at biological barriers, emphasis on diseases in tissues at the interface with the environment such as the lung, skin, gastrointestinal tract and even the neuro-immune axis are the main focus of the lab.
Current Lab Members