Find a list of our news and achievements below:
Cruse Lab collaborative work published | October 1, 2020
Cruse Lab collaborative work published | April 8, 2020
A Cruse Lab collaboration with Dr. Santosh Mishra on periostin and itch has been published in Cell Reports.
Cruse Lab publishes study identifying a role for MS4A4A in mast cell degranulation | March 30, 2020
Congratulations to Greer Arthur on her publication demonstrating an important role for MS4A4A in IgE-mediated mast cell degranulation and store-operated calcium entry through Orai1. This study published in the journal Cellular Signalling, is an important step forwards for establishing roles for this understudied protein in immunology and a potential association with allergic diseases.
Cruse Lab collaborative work published | February 26, 2020
Cruse Lab awarded NIH R01 from NIAID | September 18, 2019
The Cruse Lab has been awarded an R01 grant from NIAID, NIH to study the Regulation of FcεRI function by the MS4A gene cluster! For details about this project see the molecular mechanisms section of our research. We are looking for motivated people with an interest in molecular and mast cell biology to join this project.
Congratulations to Lauren | June 29, 2019
After 3 years in the Cruse lab, Lauren is leaving to study in the MD program at Wake Forest medical school. Thank you for all of your hard work over the last 3 years and best of luck in your new career!
Greer’s last day in the lab | September 18, 2018
After 2 years in the Cruse lab, Greer is leaving to join Dr. Thakur as the new communications and program specialist for the Global Health Program at CVM. Best of luck for the future!!
New Publication | September 2, 2018
Today, we published our methods of exon skipping in mast cells, and the assays we use to examine the responses of mast cells in vitro and in vivo. Find the article here.
2018 CMI Symposium | NC State
Congratulations to Jen and Doug for presenting their posters at the 2018 CMI Symposium, hopefully the first of many presentations for their joint work on drug delivery.
2018 CMI Symposium | NC State
Congratulations to Ariana for presenting her poster at the 2018 CMI Symposium and winning second prize for her SIRI project!
Immunology 2018 | Austin, TX
Congratulations to Greer for presenting her work “Roles for MS4A4 in FcεRI signal transduction and store-operated calcium entry in human mast cells” at the 2018 AAI conference in Austin, TX, and receiving a 2018 AAI Trainee Poster Award!
Young Scholar Award | CMI, 2018
Congratulations to Greer and Doug for teaming up with Emily Wrona (Freytes Lab) and Greg Krane (Breen Lab) and winning a Young Scholar Award! Together, they put together a proposal for a summer research project as part of the CMI’s SIRI program. With the award, they will receive a summer stipend for an undergraduate student. Project Title: Development of a Three-Dimensional In Vitro Model of Mast Cell Neoplasia.
CVM Research Forum | September 22, 2017
Greer and Lauren presented their research on MS4A proteins at the 2017 CVM Research Day & Litwack Lecture today. Find out more about this project on our Research page.
In: Veterinary Medicine News | April 26, 2017
Article: Attacking Allergies at their Source
Dr. Cruse discusses his recent work on antisense oligonucleotides and the IgE receptor, published in PNAS (Pubmed), and the implications for allergic diseases.
In: Journal of Allergy and Clinical Immunology | February, 2017
In: World Allergy Organization | December, 2016
New Publication in PNAS | December 6, 2016
Today, we published the findings of our study that investigated the use of antisense oligonucleotides for eliminating expression of the β-subunit of the high-affinity IgE receptor (FcεRIβ) in mast cells. Find the article here.
In: Medical Xpress | November, 2016